Screening of urine identifies PLA2G16 as a field defect methylation biomarker for prostate cancer detection

BACKGROUND: Prostate cancer (PC) is a multifocal disease. DNA methylation alterations are not restricted to the immediate peritumor environment, but spatially widespread in the adjacent and distant histologically normal prostate tissues. In the current study, we utilized high-throughput methylation...

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Bibliographic Details
Published in:PLoS One
Main Authors: Jarrard, William E., Schultz, Adam, Etheridge, Tyler, Damodaran, Shivashankar, Allen, Glenn O., Jarrard, David, Yang, Bing
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590820/
https://ncbi.nlm.nih.gov/pubmed/31233548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218950
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