Mycophenolate Mofetil Treatment of Systemic Sclerosis Reduces Myeloid Cell Numbers and Attenuates the Inflammatory Gene Signature in Skin

Fewer than half of patients with systemic sclerosis demonstrate modified Rodnan skin score improvement during mycophenolate mofetil (MMF) treatment. To understand the molecular basis for this observation, we extended our prior studies and characterized molecular and cellular changes in skin biopsies...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Invest Dermatol
Hauptverfasser: Hinchcliff, Monique, Toledo, Diana M., Taroni, Jaclyn N., Wood, Tammara A., Franks, Jennifer M., Ball, Michael S., Hoffmann, Aileen, Amin, Sapna M., Tan, Ainah U., Tom, Kevin, Nesbeth, Yolanda, Lee, Jungwha, Ma, Madeleine, Aren, Kathleen, Carns, Mary A., Pioli, Patricia A., Whitfield, Michael L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590516/
https://ncbi.nlm.nih.gov/pubmed/29391252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2018.01.006
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge