Mycophenolate Mofetil Treatment of Systemic Sclerosis Reduces Myeloid Cell Numbers and Attenuates the Inflammatory Gene Signature in Skin

Fewer than half of patients with systemic sclerosis demonstrate modified Rodnan skin score improvement during mycophenolate mofetil (MMF) treatment. To understand the molecular basis for this observation, we extended our prior studies and characterized molecular and cellular changes in skin biopsies...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Hinchcliff, Monique, Toledo, Diana M., Taroni, Jaclyn N., Wood, Tammara A., Franks, Jennifer M., Ball, Michael S., Hoffmann, Aileen, Amin, Sapna M., Tan, Ainah U., Tom, Kevin, Nesbeth, Yolanda, Lee, Jungwha, Ma, Madeleine, Aren, Kathleen, Carns, Mary A., Pioli, Patricia A., Whitfield, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590516/
https://ncbi.nlm.nih.gov/pubmed/29391252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2018.01.006
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