Pharmacokinetics and pharmacodynamics of dapagliflozin in combination with insulin in Japanese patients with type 1 diabetes

AIMS: To assess the pharmacokinetics/pharmacodynamics (PK/PD) of dapagliflozin, a sodium‐glucose co‐transporter 2 inhibitor that increases urinary glucose excretion (UGE) and its major metabolite, dapagliflozin‐3‐O‐glucuronide (D3OG), in Japanese patients with type 1 diabetes (T1D) and inadequate gl...

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Bibliographic Details
Published in:Diabetes Obes Metab
Main Authors: Watada, Hirotaka, Shiramoto, Masanari, Ueda, Shinya, Tang, Weifeng, Asano, Michiko, Thorén, Fredrik, Kim, Hyosung, Yajima, Toshitaka, Boulton, David W., Araki, Eiichi
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2018
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590304/
https://ncbi.nlm.nih.gov/pubmed/30499157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.13593
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