Intraductal patient‐derived xenografts of estrogen receptor α‐positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions

Estrogen receptor α‐positive (ER‐positive) or ‘luminal’ breast cancers were notoriously difficult to establish as patient‐derived xenografts (PDXs). We and others recently demonstrated that the microenvironment is critical for ER‐positive tumor cells; when grafted as single cells into milk ducts of...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Fiche, Maryse, Scabia, Valentina, Aouad, Patrick, Battista, Laura, Treboux, Assia, Stravodimou, Athina, Zaman, Khalil, Dormoy, Valerian, Ayyanan, Ayyakkannu, Sflomos, George, Brisken, Cathrin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2018
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590246/
https://ncbi.nlm.nih.gov/pubmed/30430577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5200
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