Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium

Oestrogen receptor α (ERα) is a transcription factor with ligand-independent and ligand-dependent activation functions (AF)-1 and -2. Oestrogens control postnatal mammary gland development acting on a subset of mammary epithelial cells (MECs), termed sensor cells, which are ERα-positive by immunohis...

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Udgivet i:Nat Commun
Main Authors: Cagnet, Stéphanie, Ataca, Dalya, Sflomos, George, Aouad, Patrick, Schuepbach-Mallepell, Sonia, Hugues, Henry, Krust, Andrée, Ayyanan, Ayyakkannu, Scabia, Valentina, Brisken, Cathrin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226531/
https://ncbi.nlm.nih.gov/pubmed/30413705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07175-0
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