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Paracrine signaling through the epithelial estrogen receptor α is required for proliferation and morphogenesis in the mammary gland

Estradiol is a major regulator of postnatal mammary gland development and thought to exert its effects through estrogen receptor α (ERα) expressed in the mammary gland stroma and epithelium. Previous studies, however, were confounded by the use of an ERα mutant strain that retains some of the protei...

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Main Authors: Mallepell, Sonia, Krust, Andrée, Chambon, Pierre, Brisken, Cathrin
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413744/
https://ncbi.nlm.nih.gov/pubmed/16452162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510974103
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