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Optimization of Receptor Occupancy Assays in Mass Cytometry: Standardization Across Channels with QSC Beads
Receptor occupancy, the ratio between amount of drug bound and amount of total receptor on single cells, is a biomarker for treatment response to therapeutic monoclonal antibodies. Receptor occupancy is traditionally measured by flow cytometry. However, spectral overlap in flow cytometry limits the...
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| Publicado no: | Cytometry A |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6590231/ https://ncbi.nlm.nih.gov/pubmed/30688025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.23723 |
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