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Identification of pathogenic YY1AP1 splice variants in siblings with Grange syndrome by whole exome sequencing

Grange syndrome is an autosomal recessive condition characterized by arterial occlusions and hypertension. Syndactyly, brachydactyly, bone fragility, heart defects, and learning disabilities have also been reported. Loss‐of‐function variants in YY1AP1 have only recently been associated with Grange s...

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Detalhes bibliográficos
Publicado no:Am J Med Genet A
Main Authors: Rath, Matthias, Spiegler, Stefanie, Strom, Tim M., Trenkler, Johannes, Kroisel, Peter Michael, Felbor, Ute
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590215/
https://ncbi.nlm.nih.gov/pubmed/30556293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.60700
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