Dupilumab reduces local type 2 pro‐inflammatory biomarkers in chronic rhinosinusitis with nasal polyposis

BACKGROUND: Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a type 2‐mediated inflammatory disease associated with significant clinical, social, and economic burdens and high unmet therapeutic need. Dupilumab, a fully human monoclonal antibody targeting the interleukin‐4 receptor α (IL‐4Rα)...

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Dades bibliogràfiques
Publicat a:Allergy
Autors principals: Jonstam, Karin, Swanson, Brian N., Mannent, Leda P., Cardell, Lars‐Olaf, Tian, Nian, Wang, Ying, Zhang, Donghui, Fan, Chunpeng, Holtappels, Gabriele, Hamilton, Jennifer D., Grabher, Annette, Graham, Neil M. H., Pirozzi, Gianluca, Bachert, Claus
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
ORIGINAL ARTICLES
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590149/
https://ncbi.nlm.nih.gov/pubmed/30488542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.13685
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