Population Pharmacokinetic Modeling of Acetaminophen and Metabolites in Children After Cardiac Surgery With Cardiopulmonary Bypass

Children undergoing cardiac surgery often receive acetaminophen (paracetamol) as part of their postoperative pain treatment. To date, there is no information on the pharmacokinetics (PK) of acetaminophen in this special population, even though differences, as a result of altered hemodynamics and/or...

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Bibliografski detalji
Izdano u:J Clin Pharmacol
Glavni autori: Mian, P., Valkenburg, A.J., Allegaert, K., Koch, B.C.P., Breatnach, C.V., Knibbe, C.A.J., Tibboel, D., Krekels, E.H.J.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Pediatric Pharmacology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590134/
https://ncbi.nlm.nih.gov/pubmed/30633373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1373
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