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Ataluren Pharmacokinetics in Healthy Japanese and Caucasian Subjects

To evaluate the potential for ethnicity‐related differences in ataluren pharmacokinetics (PK) and safety, a phase 1 single‐dose study was conducted in 48 healthy (24 Japanese and 24 Caucasian subjects), nonsmoking male volunteers who were equally divided into 3 cohorts of oral doses at 5, 10, and 20...

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Détails bibliographiques
Publié dans:Clin Pharmacol Drug Dev
Auteurs principaux: Kong, Ronald, Laskin, Oscar L., Kaushik, Diksha, Jin, Fengbin, Ma, Jiyuan, McIntosh, Joseph, Souza, Marcio, Almstead, Neil
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590116/
https://ncbi.nlm.nih.gov/pubmed/30629861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.645
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