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Boundary mode lubrication of articular cartilage with a biomimetic diblock copolymer

We report the design of a diblock copolymer with architecture and function inspired by the lubricating glycoprotein lubricin. This diblock copolymer, synthesized by sequential reversible addition–fragmentation chain-transfer polymerization, consists of a cationic cartilage-binding domain and a brush...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sun, Zhexun, Feeney, Elizabeth, Guan, Ya, Cook, Sierra G., Gourdon, Delphine, Bonassar, Lawrence J., Putnam, David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589671/
https://ncbi.nlm.nih.gov/pubmed/31164421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1900716116
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