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Galectin-3 Binds to Lubricin and Reinforces the Lubricating Boundary Layer of Articular Cartilage

Lubricin is a mucinous, synovial fluid glycoprotein that enables near frictionless joint motion via adsorption to the surface of articular cartilage and its lubricating properties in solution. Extensive O-linked glycosylation within lubricin’s mucin-rich domain is critical for its boundary lubricati...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Reesink, Heidi L., Bonnevie, Edward D., Liu, Sherry, Shurer, Carolyn R., Hollander, Michael J., Bonassar, Lawrence J., Nixon, Alan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860590/
https://ncbi.nlm.nih.gov/pubmed/27157803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25463
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