Differential effects of intrauterine growth restriction and a hypersinsulinemic-isoglycemic clamp on metabolic pathways and insulin action in the fetal liver

Intrauterine growth-restricted (IUGR) fetal sheep have increased hepatic glucose production (HGP) that is resistant to suppression during a hyperinsulinemic-isoglycemic clamp (insulin clamp). We hypothesized that the IUGR fetal liver would have activation of metabolic and signaling pathways that sup...

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Foilsithe in:Am J Physiol Regul Integr Comp Physiol
Main Authors: Jones, Amanda K., Brown, Laura D., Rozance, Paul J., Serkova, Natalie J., Hay, William W., Friedman, Jacob E., Wesolowski, Stephanie R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2019
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589601/
https://ncbi.nlm.nih.gov/pubmed/30758974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00359.2018
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