The motor protein Myo1c regulates transforming growth factor-β-signaling and fibrosis in podocytes

Transforming growth factor-β (TGF-β) is known to play a critical role in the pathogenesis of many progressive podocyte diseases. However, the molecular mechanisms regulating TGF-β signaling in podocytes remain unclear. Using a podocyte-specific Myo1c knockout, we demonstrate whether Myo1c is critica...

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Veröffentlicht in:Kidney Int
Hauptverfasser: Arif, Ehtesham, Solanki, Ashish K., Srivastava, Pankaj, Rahman, Bushra, Tash, Brian R, Holzman, Lawrence B, Janech, Michael G, Martin, René, Knölken, Hans-Joachim, Fitzgibbon, Wayne R., Deng, Peifeng, Budisavljevic, Milos N., Syn, Wing-Kin, Wang, Cindy, Lipschutz, Joshua H., Kwon, Sang-Ho, Nihalani, Deepak
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589397/
https://ncbi.nlm.nih.gov/pubmed/31097328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2019.02.014
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