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Elucidating Relayed Proton Transfer Through a His-Trp- His Triad of a Transmembrane Proton Channel by Solid-State NMR
Proton transfer in membrane-bound ion channels is mediated by both water and polar residues of proteins, but the detailed molecular mechanism is challenging to determine. The tetrameric influenza A and B virus M2 proteins form canonical proton channels that use an HxxxW motif for proton selectivity...
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| 出版年: | J Mol Biol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6589385/ https://ncbi.nlm.nih.gov/pubmed/31082440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.05.009 |
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