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Thioesterase-catalyzed aminoacylation and thiolation of polyketides in fungi

Fungal highly reducing polyketide synthases (HRPKSs) biosynthesize polyketides using a single set of domains iteratively. Product release is a critical step in HRPKS function to ensure timely termination and enzyme turnover. Nearly all of the HRPKSs characterized to date employ a separate thioestera...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Am Chem Soc
Egile Nagusiak: Tang, Man-Cheng, Fischer, Curt R., Chari, Jason V., Tan, Dan, Suresh, Sundari, Chu, Angela, Miranda, Molly, Smith, Justin, Zhang, Zhuan, Garg, Neil K., Onge, Robert P., Tang, Yi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589186/
https://ncbi.nlm.nih.gov/pubmed/31051070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b01083
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