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Thioesterase-catalyzed aminoacylation and thiolation of polyketides in fungi
Fungal highly reducing polyketide synthases (HRPKSs) biosynthesize polyketides using a single set of domains iteratively. Product release is a critical step in HRPKS function to ensure timely termination and enzyme turnover. Nearly all of the HRPKSs characterized to date employ a separate thioestera...
Gorde:
Argitaratua izan da: | J Am Chem Soc |
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Egile Nagusiak: | , , , , , , , , , , , |
Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
2019
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6589186/ https://ncbi.nlm.nih.gov/pubmed/31051070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b01083 |
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