β1 integrin is a sensor of blood flow direction

Endothelial cell (EC) sensing of fluid shear stress direction is a critical determinant of vascular health and disease. Unidirectional flow induces EC alignment and vascular homeostasis, whereas bidirectional flow has pathophysiological effects. ECs express several mechanoreceptors that respond to f...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Xanthis, Ioannis, Souilhol, Celine, Serbanovic-Canic, Jovana, Roddie, Hannah, Kalli, Antreas C., Fragiadaki, Maria, Wong, Raymond, Shah, Dhruv R., Askari, Janet A., Canham, Lindsay, Akhtar, Nasreen, Feng, Shuang, Ridger, Victoria, Waltho, Jonathan, Pinteaux, Emmanuel, Humphries, Martin J., Bryan, Matthew T., Evans, Paul C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589088/
https://ncbi.nlm.nih.gov/pubmed/31076511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.229542
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