Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail

Blood flow influences atherosclerosis by generating wall shear stress, which alters endothelial cell (EC) physiology. Low shear stress induces dedifferentiation of EC through a process termed endothelial-to-mesenchymal transition (EndMT). The mechanisms underlying shear stress-regulation of EndMT ar...

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Pubblicato in:Sci Rep
Autori principali: Mahmoud, Marwa M., Serbanovic-Canic, Jovana, Feng, Shuang, Souilhol, Celine, Xing, Rouyu, Hsiao, Sarah, Mammoto, Akiko, Chen, Jing, Ariaans, Markus, Francis, Sheila E., Van der Heiden, Kim, Ridger, Victoria, Evans, Paul C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469771/
https://ncbi.nlm.nih.gov/pubmed/28611395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03532-z
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