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The HIF-1α/LC3-II Axis Impacts Fungal Immunity in Human Macrophages
The fungal pathogen Histoplasma capsulatum causes a spectrum of disease, ranging from local pulmonary infection to disseminated disease. The organism seeks residence in macrophages, which are permissive for its survival. Hypoxia-inducible factor 1α (HIF-1α), a principal regulator of innate immunity...
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| Publicat a: | Infect Immun |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6589057/ https://ncbi.nlm.nih.gov/pubmed/31036602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00125-19 |
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