Standard dose osimertinib for erlotinib refractory T790M-negative EGFR-mutant non-small cell lung cancer with leptomeningeal disease

BACKGROUND: Leptomeningeal spread in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations who experience disease progression on TKIs portends a poor prognosis. Mutation profiling of tumour DNA in cerebrospinal fluid (CSF) samples can be used to determine...

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Detalhes bibliográficos
Publicado no:J Thorac Dis
Main Authors: Arulananda, Surein, Do, Hongdo, Rivalland, Gareth, Loh, Zoe, Musafer, Ashan, Lau, Eddie, Mitchell, Paul, Dobrovic, Alexander, John, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588760/
https://ncbi.nlm.nih.gov/pubmed/31285867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2019.05.41
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