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Successful osimertinib treatment for leptomeningeal carcinomatosis from lung adenocarcinoma with the T790M mutation of EGFR

Osimertinib is a third-generation tyrosine kinase inhibitor (TKI) of the epidermal growth factor receptor (EGFR) that has been approved for the treatment of metastatic non-small cell lung cancer (NSCLC) positive for the secondary T790M mutation of EGFR. In a preclinical study, it also showed efficac...

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Detalhes bibliográficos
Publicado no:ESMO Open
Main Authors: Sakai, Hitomi, Hayashi, Hidetoshi, Iwasa, Tsutomu, Hasegawa, Yoshikazu, Takeda, Masayuki, Nakagawa, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559906/
https://ncbi.nlm.nih.gov/pubmed/28848674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2016-000104
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