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Astrocyte alterations in neurodegenerative pathologies and their modeling in human induced pluripotent stem cell platforms

Astrocytes are the most abundant cell type in the brain. They were long considered only as passive support for neuronal cells. However, recent data have revealed many active roles for these cells both in maintenance of the normal physiological homeostasis in the brain as well as in neurodegeneration...

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Podrobná bibliografie
Vydáno v:Cell Mol Life Sci
Hlavní autoři: Oksanen, Minna, Lehtonen, Sarka, Jaronen, Merja, Goldsteins, Gundars, Hämäläinen, Riikka H., Koistinaho, Jari
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588647/
https://ncbi.nlm.nih.gov/pubmed/31016348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03111-7
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