Hypoxia Prevents Mitochondrial Dysfunction and Senescence in Human c-Kit+ Cardiac Progenitor Cells

Senescence-associated dysfunction deleteriously affects biological activites of human c-Kit+ cardiac progenitor cells (hCPCs), particularly under conditions of in vitro culture. In comparison, preservation of self-renewal and decreases in mitochondrial reactive oxygen species (ROS) are characteristi...

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Vydáno v:Stem Cells
Hlavní autoři: Korski, Kelli I., Kubli, Dieter A., Wang, Bingyan J., Khalafalla, Farid G., Monsanto, Megan M., Firouzi, Fareheh, Echeagaray, Oscar H., Kim, Taeyong, Adamson, Robert M., Dembitsky, Walter P., Gustafsson, Åsa B., Sussman, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588544/
https://ncbi.nlm.nih.gov/pubmed/30629785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2970
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