Hypoxia Prevents Mitochondrial Dysfunction and Senescence in Human c-Kit+ Cardiac Progenitor Cells

Senescence-associated dysfunction deleteriously affects biological activites of human c-Kit+ cardiac progenitor cells (hCPCs), particularly under conditions of in vitro culture. In comparison, preservation of self-renewal and decreases in mitochondrial reactive oxygen species (ROS) are characteristi...

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Bibliografske podrobnosti
izdano v:Stem Cells
Main Authors: Korski, Kelli I., Kubli, Dieter A., Wang, Bingyan J., Khalafalla, Farid G., Monsanto, Megan M., Firouzi, Fareheh, Echeagaray, Oscar H., Kim, Taeyong, Adamson, Robert M., Dembitsky, Walter P., Gustafsson, Åsa B., Sussman, Mark A.
Format: Artigo
Jezik:Inglês
Izdano: 2019
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588544/
https://ncbi.nlm.nih.gov/pubmed/30629785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2970
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