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Heterogeneity in a large pedigree with Danon disease: Implications for pathogenesis and management

BACKGROUND: Danon disease is an X-linked disturbance of autophagy manifesting with cognitive impairment and disordered heart and skeletal muscle. After a period of relative stability, patients deteriorate rapidly and may quickly become ineligible for elective heart transplantation - the only life-sa...

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Detalhes bibliográficos
Publicado no:Mol Genet Metab
Main Authors: Roos, Jonathan C. P., Daniels, Matthew J., Morris, Elizabeth, Hyry, Hanna I., Cox, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588538/
https://ncbi.nlm.nih.gov/pubmed/28822614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2017.06.008
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