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Cyclin F controls cell cycle transcriptional outputs by directing the degradation of the three activator E2Fs

E2F1, E2F2 and E2F3A, the three activators of the E2F family of transcription factors, are key regulators of the G1/S transition, promoting transcription of hundreds of genes critical for cell cycle progression. We found that, during late S and in G2, the degradation of all three activator E2Fs is c...

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Dettagli Bibliografici
Pubblicato in:Mol Cell
Autori principali: Clijsters, Linda, Hoencamp, Claire, Calis, Jorg J. A., Marzio, Antonio, Handgraaf, Shanna M., Cuitino, Maria C., Rosenberg, Brad R., Leone, Gustavo, Pagano, Michele
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588466/
https://ncbi.nlm.nih.gov/pubmed/31130363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.04.010
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