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Cyclin F controls cell cycle transcriptional outputs by directing the degradation of the three activator E2Fs

E2F1, E2F2 and E2F3A, the three activators of the E2F family of transcription factors, are key regulators of the G1/S transition, promoting transcription of hundreds of genes critical for cell cycle progression. We found that, during late S and in G2, the degradation of all three activator E2Fs is c...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Clijsters, Linda, Hoencamp, Claire, Calis, Jorg J. A., Marzio, Antonio, Handgraaf, Shanna M., Cuitino, Maria C., Rosenberg, Brad R., Leone, Gustavo, Pagano, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588466/
https://ncbi.nlm.nih.gov/pubmed/31130363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.04.010
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