Disease-associated mutations in human TUBB3 disturb netrin repulsive signaling

Missense mutations in the human TUBB3 gene cause a variety of neurological disorders associated with defects in axon guidance and neuronal migration, but the underlying molecular mechanisms are not well understood. Recent studies have shown that direct coupling of dynamic TUBB3 in microtubules with...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Shao, Qiangqiang, Yang, Tao, Huang, Huai, Majumder, Tanushree, Khot, Bhakti Ajit, Khouzani, Mohammad Masoudian, Alarmanazi, Farrah, Gore, Yasmin K., Liu, Guofa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588280/
https://ncbi.nlm.nih.gov/pubmed/31226147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218811
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