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Disease-associated mutations in human TUBB3 disturb netrin repulsive signaling

Missense mutations in the human TUBB3 gene cause a variety of neurological disorders associated with defects in axon guidance and neuronal migration, but the underlying molecular mechanisms are not well understood. Recent studies have shown that direct coupling of dynamic TUBB3 in microtubules with...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Shao, Qiangqiang, Yang, Tao, Huang, Huai, Majumder, Tanushree, Khot, Bhakti Ajit, Khouzani, Mohammad Masoudian, Alarmanazi, Farrah, Gore, Yasmin K., Liu, Guofa
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588280/
https://ncbi.nlm.nih.gov/pubmed/31226147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218811
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