Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites

Malaria is caused by Plasmodium parasites, which invade and replicate in erythrocytes. For Plasmodium falciparum, the major cause of severe malaria in humans, a heterotrimeric complex comprised of the secreted parasite proteins, PfCyRPA, PfRIPR and PfRH5 is essential for erythrocyte invasion, mediat...

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發表在:PLoS Pathog
Main Authors: Knuepfer, Ellen, Wright, Katherine E., Kumar Prajapati, Surendra, Rawlinson, Thomas A., Mohring, Franziska, Koch, Marion, Lyth, Oliver R., Howell, Steven A., Villasis, Elizabeth, Snijders, Ambrosius P., Moon, Robert W., Draper, Simon J., Rosanas-Urgell, Anna, Higgins, Matthew K., Baum, Jake, Holder, Anthony A.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2019
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588255/
https://ncbi.nlm.nih.gov/pubmed/31185066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007809
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