Neutralising antibodies block the function of Rh5/Ripr/CyRPA complex during invasion of Plasmodium falciparum into human erythrocytes

An effective vaccine is a priority for malaria control and elimination. The leading candidate in the Plasmodium falciparum blood stage is PfRh5. PfRh5 assembles into trimeric complex with PfRipr and PfCyRPA in the parasite, and this complex is essential for erythrocyte invasion. In this study, we sh...

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Detalles Bibliográficos
Publicado en:Cell Microbiol
Main Authors: Healer, Julie, Wong, Wilson, Thompson, Jennifer K., He, Wengqiang, Birkinshaw, Richard W., Miura, Kazutoyo, Long, Carol A., Soroka, Vladislav, Søgaard, Teit Max Moscote, Jørgensen, Thomas, de Jongh, Willem A., Weir, Christopher, Svahn, Ella, Czabotar, Peter E., Tham, Wai‐Hong, Mueller, Ivo, Barlow, Paul N., Cowman, Alan F.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594224/
https://ncbi.nlm.nih.gov/pubmed/30965383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.13030
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