Alternative splicing expands the prognostic impact of KRAS in microsatellite stable primary colorectal cancer

KRAS mutation is a well‐known marker for poor response to targeted treatment and patient prognosis in microsatellite stable (MSS) colorectal cancer (CRC). However, variation in clinical outcomes among patients wild‐type for KRAS underlines that this is not a homogeneous population. Here, we evaluate...

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Udgivet i:Int J Cancer
Main Authors: Eilertsen, Ina A., Sveen, Anita, Strømme, Jonas M., Skotheim, Rolf I., Nesbakken, Arild, Lothe, Ragnhild A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2018
Fag:
Tumor Markers and Signatures
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587976/
https://ncbi.nlm.nih.gov/pubmed/30121958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31809
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