Expression of STAT3-regulated genes in circulating CD4+ T cells discriminates rheumatoid arthritis independently of clinical parameters in early arthritis

OBJECTIVES: Dysregulated signal transduction and activator of transcription-3 (STAT3) signalling in CD4+ T cells has been proposed as an early pathophysiological event in RA. We sought further evidence for this observation, and to determine its clinical relevance. METHODS: Microarray technology was...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Rheumatology (Oxford)
Hlavní autoři: Anderson, Amy E, Maney, Nicola J, Nair, Nisha, Lendrem, Dennis W, Skelton, Andrew J, Diboll, Julie, Brown, Philip M, Smith, Graham R, Carmody, Ruaidhrí J, Barton, Anne, Isaacs, John D, Pratt, Arthur G
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Clinical Science
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587924/
https://ncbi.nlm.nih.gov/pubmed/30753680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kez003
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky