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Detection and accurate false discovery rate control of differentially methylated regions from whole genome bisulfite sequencing

With recent advances in sequencing technology, it is now feasible to measure DNA methylation at tens of millions of sites across the entire genome. In most applications, biologists are interested in detecting differentially methylated regions, composed of multiple sites with differing methylation le...

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Detalhes bibliográficos
Publicado no:Biostatistics
Main Authors: Korthauer, Keegan, Chakraborty, Sutirtha, Benjamini, Yuval, Irizarry, Rafael A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587918/
https://ncbi.nlm.nih.gov/pubmed/29481604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxy007
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