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Genotype and phenotype variability in Sjögren‐Larsson syndrome

The Sjögren–Larsson syndrome (SLS) is a rare autosomal recessive disorder caused by pathogenic variants in the ALDH3A2 gene, which codes for fatty aldehyde dehydrogenase (FALDH). FALDH prevents the accumulation of toxic fatty aldehydes by converting them into fatty acids. Pathogenic ALDH3A2 variants...

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Dades bibliogràfiques
Publicat a:Hum Mutat
Autors principals: Weustenfeld, Maximilian, Eidelpes, Reiner, Schmuth, Matthias, Rizzo, William B., Zschocke, Johannes, Keller, Markus A.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587760/
https://ncbi.nlm.nih.gov/pubmed/30372562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23679
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