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Genotype and phenotype variability in Sjögren‐Larsson syndrome

The Sjögren–Larsson syndrome (SLS) is a rare autosomal recessive disorder caused by pathogenic variants in the ALDH3A2 gene, which codes for fatty aldehyde dehydrogenase (FALDH). FALDH prevents the accumulation of toxic fatty aldehydes by converting them into fatty acids. Pathogenic ALDH3A2 variants...

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Detalhes bibliográficos
Publicado no:Hum Mutat
Main Authors: Weustenfeld, Maximilian, Eidelpes, Reiner, Schmuth, Matthias, Rizzo, William B., Zschocke, Johannes, Keller, Markus A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587760/
https://ncbi.nlm.nih.gov/pubmed/30372562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23679
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