Familial breast cancer and DNA repair genes: Insights into known and novel susceptibility genes from the GENESIS study, and implications for multigene panel testing

Pathogenic variants in BRCA1 and BRCA2 only explain the underlying genetic cause of about 10% of hereditary breast and ovarian cancer families. Because of cost‐effectiveness, multigene panel testing is often performed even if the clinical utility of testing most of the genes remains questionable. Th...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Girard, Elodie, Eon‐Marchais, Séverine, Olaso, Robert, Renault, Anne‐Laure, Damiola, Francesca, Dondon, Marie‐Gabrielle, Barjhoux, Laure, Goidin, Didier, Meyer, Vincent, Le Gal, Dorothée, Beauvallet, Juana, Mebirouk, Noura, Lonjou, Christine, Coignard, Juliette, Marcou, Morgane, Cavaciuti, Eve, Baulard, Céline, Bihoreau, Marie‐Thérèse, Cohen‐Haguenauer, Odile, Leroux, Dominique, Penet, Clotilde, Fert‐Ferrer, Sandra, Colas, Chrystelle, Frebourg, Thierry, Eisinger, François, Adenis, Claude, Fajac, Anne, Gladieff, Laurence, Tinat, Julie, Floquet, Anne, Chiesa, Jean, Giraud, Sophie, Mortemousque, Isabelle, Soubrier, Florent, Audebert‐Bellanger, Séverine, Limacher, Jean‐Marc, Lasset, Christine, Lejeune‐Dumoulin, Sophie, Dreyfus, Hélène, Bignon, Yves‐Jean, Longy, Michel, Pujol, Pascal, Venat‐Bouvet, Laurence, Bonadona, Valérie, Berthet, Pascaline, Luporsi, Elisabeth, Maugard, Christine M., Noguès, Catherine, Delnatte, Capucine, Fricker, Jean‐Pierre, Gesta, Paul, Faivre, Laurence, Lortholary, Alain, Buecher, Bruno, Caron, Olivier, Gauthier‐Villars, Marion, Coupier, Isabelle, Servant, Nicolas, Boland, Anne, Mazoyer, Sylvie, Deleuze, Jean‐François, Stoppa‐Lyonnet, Dominique, Andrieu, Nadine, Lesueur, Fabienne
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Cancer Genetics and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587727/
https://ncbi.nlm.nih.gov/pubmed/30303537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31921
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