Variation in breast cancer risk associated with factors related to pregnancies according to truncating mutation location, in the French National BRCA1 and BRCA2 mutations carrier cohort (GENEPSO)

INTRODUCTION: Mutations in BRCA1 and BRCA2 confer a high risk of breast cancer (BC), but the magnitude of this risk seems to vary according to the study and various factors. Although controversial, there are data to support the hypothesis of allelic risk heterogeneity. METHODS: We assessed variation...

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Main Authors: Lecarpentier, Julie, Noguès, Catherine, Mouret-Fourme, Emmanuelle, Gauthier-Villars, Marion, Lasset, Christine, Fricker, Jean-Pierre, Caron, Olivier, Stoppa-Lyonnet, Dominique, Berthet, Pascaline, Faivre, Laurence, Bonadona, Valérie, Buecher, Bruno, Coupier, Isabelle, Gladieff, Laurence, Gesta, Paul, Eisinger, François, Frénay, Marc, Luporsi, Elisabeth, Lortholary, Alain, Colas, Chrystelle, Dugast, Catherine, Longy, Michel, Pujol, Pascal, Tinat, Julie, Lidereau, Rosette, Andrieu, Nadine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680948/
https://ncbi.nlm.nih.gov/pubmed/22762150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3218
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