Eosinophilia and reduced STAT3 signaling affect neutrophil cell death in autosomal‐dominant Hyper‐IgE syndrome

The autosomal‐dominant hyper‐IgE syndrome (HIES), caused by mutations in STAT3, is a rare primary immunodeficiency that predisposes to mucocutaneous candidiasis and staphylococcal skin and lung infections. This infection phenotype is suggestive of defects in neutrophils, but data on neutrophil funct...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Eur J Immunol
Päätekijät: Farmand, Susan, Kremer, Bernhard, Häffner, Monika, Pütsep, Katrin, Bergman, Peter, Sundin, Mikael, Ritterbusch, Henrike, Seidl, Maximilian, Follo, Marie, Henneke, Philipp, Henriques‐Normark, Birgitta
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Immunity to infection
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587726/
https://ncbi.nlm.nih.gov/pubmed/30315710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201847650
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