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Exploring Rigid and Flexible Core Trivalent Sialosides for Influenza Virus Inhibition

Herein, the chemical synthesis and binding analysis of functionalizable rigid and flexible core trivalent sialosides bearing oligoethylene glycol (OEG) spacers interacting with spike proteins of influenza A virus (IAV) X31 is described. Although the flexible Tris‐based trivalent sialosides achieved...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Kiran, Pallavi, Bhatia, Sumati, Lauster, Daniel, Aleksić, Stevan, Fleck, Carsten, Peric, Natalija, Maison, Wolfgang, Liese, Susanne, Keller, Bettina G., Herrmann, Andreas, Haag, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587447/
https://ncbi.nlm.nih.gov/pubmed/30295350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201804826
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