A population pharmacokinetic study of benzathine benzylpenicillin G administration in children and adolescents with rheumatic heart disease: new insights for improved secondary prophylaxis strategies

BACKGROUND: Benzathine benzylpenicillin G (BPG) is recommended as secondary prophylaxis to prevent recurrence of acute rheumatic fever and subsequent rheumatic heart disease (RHD). Following intramuscular injection, BPG is hydrolysed to benzylpenicillin. Little is known of the pharmacokinetics of be...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Antimicrob Chemother
Main Authors: Hand, Robert M, Salman, Sam, Newall, Nelly, Vine, Julie, Page-Sharp, Madhu, Bowen, Asha C, Gray, Katherine, Baker, Amy, Kado, Joseph, Joseph, John, Marsh, Julie, Ramsay, James, Sika-Paotonu, Dianne, Batty, Kevin T, Manning, Laurens, Carapetis, Jonathan
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587412/
https://ncbi.nlm.nih.gov/pubmed/30989171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkz076
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki