A population pharmacokinetic study of benzathine benzylpenicillin G administration in children and adolescents with rheumatic heart disease: new insights for improved secondary prophylaxis strategies

BACKGROUND: Benzathine benzylpenicillin G (BPG) is recommended as secondary prophylaxis to prevent recurrence of acute rheumatic fever and subsequent rheumatic heart disease (RHD). Following intramuscular injection, BPG is hydrolysed to benzylpenicillin. Little is known of the pharmacokinetics of be...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Hand, Robert M, Salman, Sam, Newall, Nelly, Vine, Julie, Page-Sharp, Madhu, Bowen, Asha C, Gray, Katherine, Baker, Amy, Kado, Joseph, Joseph, John, Marsh, Julie, Ramsay, James, Sika-Paotonu, Dianne, Batty, Kevin T, Manning, Laurens, Carapetis, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587412/
https://ncbi.nlm.nih.gov/pubmed/30989171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkz076
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados