Melatonin enhances sorafenib-induced cytotoxicity in FLT3-ITD acute myeloid leukemia cells by redox modification

Acute myeloid leukemia (AML) with an internal tandem duplication in Fms-related tyrosine kinase 3 (FLT3-ITD) is identified as a subgroup with poor outcome and intrinsic resistance to chemotherapy and therefore urgent need for development of novel therapeutic strategies. Methods: The antitumor effect...

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Tian, Tian, Li, Jiajun, Li, Yizhuo, Lu, Yun-Xin, Tang, Yan-Lai, Wang, Hua, Zheng, Fufu, Shi, Dingbo, Long, Qian, Chen, Miao, Garcia-Manero, Guillermo, Hu, Yumin, Qin, Lijun, Deng, Wuguo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587355/
https://ncbi.nlm.nih.gov/pubmed/31281512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.34327
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