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IL-21-based therapies induce clearance of hepatitis B virus persistence in mouse models
Chronic hepatitis B virus (HBV) infection causes hepatitis, liver cirrhosis and hepatocellular carcinoma. Covalently closed circular DNA (cccDNA) is the sole viral transcription template and not affected by current treatment options, constituting a key determinant of HBV persistence. Novel therapeut...
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| Опубликовано в: : | Theranostics |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Ivyspring International Publisher
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6587353/ https://ncbi.nlm.nih.gov/pubmed/31281514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.35331 |
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