Non-classical estrogen signaling in ovarian cancer improves chemo-sensitivity and patients outcome

Deficiency in homologous recombination repair (HRR) is frequently associated with hormone-responsive cancers, especially the epithelial ovarian cancer (EOC) which shows defects of HRR in up to half of cases. However, whether there are molecular connections between estrogen signaling and HRR deficien...

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Udgivet i:Theranostics
Main Authors: Hao, Dapeng, Li, Jingjing, Wang, Jianlin, Meng, Yuan, Zhao, Zhiqiang, Zhang, Chao, Miao, Kai, Deng, Chuxia, Tsang, Benjamin K., Wang, Li, Di, Li-jun
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587348/
https://ncbi.nlm.nih.gov/pubmed/31281524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.30814
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