SB225002 Promotes Mitotic Catastrophe in Chemo-Sensitive and -Resistant Ovarian Cancer Cells Independent of p53 Status In Vitro

Recent evidence indicates that CXCR2 signaling is crucial for cancer progression, and its antagonist SB225002 induces apoptosis in Wilms’ tumor cells. Here, we investigated the effect of SB225002 on cell cycle progression and apoptosis induction in vitro, using CDDP-sensitive and -resistant OVCA cel...

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Bibliografiska uppgifter
Huvudupphovsmän: Du, Meirong, Qiu, Qing, Gruslin, Andree, Gordon, John, He, Miao, Chan, Chi Chung, Li, Dajin, Tsang, Benjamin K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554720/
https://ncbi.nlm.nih.gov/pubmed/23359652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054572
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