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Suppression of YAP/TAZ-Notch1-NICD axis by bromodomain and extraterminal protein inhibition impairs liver regeneration

Background and aims: Biological mechanisms that control liver regeneration remain poorly defined. However, these mechanisms are remarkable issues in the clinic that affect management of hepatic loss caused by liver surgery, traumatic injury, chronic infection, or liver poisoning. Increasing evidence...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Liu, Chen, Cheng, Xiawei, Chen, Juntao, Wang, Yao, Wu, Xiaoying, Tian, Rui, Liu, Baoqing, Ding, Xianfeng, Sun, Qiming, Gong, Weihua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587347/
https://ncbi.nlm.nih.gov/pubmed/31281517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.33370
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