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A subtype of oral, laryngeal, esophageal, and lung, squamous cell carcinoma with high levels of TrkB-T1 neurotrophin receptor mRNA

BACKGROUND: The NTRK2 genetic locus encodes neurotrophin membrane receptors that play an important role in normal neural tissue plasticity, growth, and survival. One NTRK2-encoded protein is TrkB-FL, which can regulate multiple pathways relevant to cancer. A second NTRK2 gene mRNA isoform encodes Tr...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Zhou, Yalu, Sinha, Saurabh, Schwartz, Joel L., Adami, Guy R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587277/
https://ncbi.nlm.nih.gov/pubmed/31221127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5789-8
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