Coro2b, a podocyte protein downregulated in human diabetic nephropathy, is involved in the development of protamine sulphate-induced foot process effacement

Podocytes have an important role in the pathogenesis of diabetic nephropathy (DN). Podocyte foot process effacement, mediated largely by the actin-based cytoskeleton of foot processes, is commonly detected in DN and is believed to be a key pathogenic event in the development of proteinuria. In this...

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Publicado en:Sci Rep
Autores principales: Schwarz, Angelina, Möller-Hackbarth, Katja, Ebarasi, Lwaki, Unnersjö Jess, David, Zambrano, Sonia, Blom, Hans, Wernerson, Annika, Lal, Mark, Patrakka, Jaakko
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586875/
https://ncbi.nlm.nih.gov/pubmed/31221975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45303-y
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