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Inactivation of mediator complex protein 22 in podocytes results in intracellular vacuole formation, podocyte loss and premature death

Podocytes are critical for the maintenance of kidney ultrafiltration barrier and play a key role in the progression of glomerular diseases. Although mediator complex proteins have been shown to be important for many physiological and pathological processes, their role in kidney tissue has not been s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rodriguez, Patricia Q., Unnersjö-Jess, David, Zambrano, Sonia S., Guo, Jing, Möller-Hackbarth, Katja, Blom, Hans, Jahnukainen, Timo, Ebarasi, Lwaki, Patrakka, Jaakko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7676236/
https://ncbi.nlm.nih.gov/pubmed/33208756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76870-0
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