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Hypoxia signaling in human diseases and therapeutic targets

Since the discovery of hypoxia-inducible factor (HIF), numerous studies on the hypoxia signaling pathway have been performed. The role of HIF stabilization during hypoxia has been extended from the induction of a single gene erythropoietin to the upregulation of a couple of hundred downstream target...

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Bibliographic Details
Published in:Exp Mol Med
Main Authors: Lee, Jae W., Ko, Junsuk, Ju, Cynthia, Eltzschig, Holger K.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586801/
https://ncbi.nlm.nih.gov/pubmed/31221962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0235-1
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